Anti-Cytokeratin 10 antibody [EP1607IHCY] - Cytoskeleton Marker,Abcam,AB76318

Anti-Cytokeratin 10 antibody [EP1607IHCY] - Cytoskeleton Marker (ab76318) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in ICC/IF, IHC-P, WB in human, mouse, rat samples. Anti-Cytokeratin 10 antibody [EP1607IHCY] - Cytoskeleton Marker (ab76318) has been cited over 129 times in peer reviewed journals and is trusted by the scientific community. Abcams high quality manufacturing and validation processes ensure Anti-Cytokeratin 10 antibody [EP1607IHCY] - Cytoskeleton Marker (ab76318) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. Anti-Cytokeratin 10 antibody [EP1607IHCY] - Cytoskeleton Marker (ab76318) has 13 independent reviews from customers. Anti-Cytokeratin 10 antibody [EP1607IHCY] - Cytoskeleton Marker (ab76318) specifically detects Cytokeratin 10 (UniProt ID: P13645; Molecular weight: 59kDa) and is sold in 100 uL and 1 mL selling sizes. Conjugation-ready, carrier free format available for antibody clone EP1607IHCY - ab2286 . Antibody clone EP1607IHCY is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor® 647, HRP ( ab194231 , ab194232 ). Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Mouse, Rat, Human

Application

ICC/IF, WB, IHC-P

Platform ID

BAB338493061

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Cytokeratin 10 antibody [EP1607IHCY] - Cytoskeleton Marker
Cat. No.AB76318
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationICC/IF, WB, IHC-P
ClonalityMonoclonal
Clone NumberEP1607IHCY
Concentration0.415 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Plays a role in the establishment of the epidermal barrier on plantar skin (By similarity). Involved in the maintenance of cell layer development and keratin filament bundles in suprabasal cells of the epithelium (By similarity).. (Microbial infection) Acts as a mediator of S.aureus adherence to desquamated nasal epithelial cells via clfB, and hence may play a role in nasal colonization.. (Microbial infection) Binds S.pneumoniae PsrP, mediating adherence of the bacteria to lung cell lines. Reduction of levels of KRT10 keratin decrease adherence, overexpression increases adherence. Neither protein has to be glycosylated for the interaction to occur. See full target information KRT10

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