Anti-Cytokeratin 18 antibody [C-04],Abcam,AB668
What is this antibody validated in? Anti-Cytokeratin 18 antibody [C-04] (ab668) is a mouse monoclonal antibody and is validated for use in Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunohistochemistry (IHC-P) in Human, Mammals samples. Trusted by the scientific community Anti-Cytokeratin 18 [C-04] (ab668) was first used in a scientific publication in 2002 and has been cited over 160 times in peer-reviewed journals. Reviewed by scientists Anti-Cytokeratin 18 [C-04] (ab668) has over 25 independent reviews from customers. Other related products We have a range of other formats of antibody clone [C-04] also available for your convenience: ab668, Biotin - ab27553 , FITC - ab52459
Host
Mouse
Reactivity
Human, Mammals
Application
IHC-P, Flow Cyt (Intra)
Platform ID
BAB401374128
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Required for the formation of KRT8/KRT18 filaments that are involved in ARHGEF40-mediated actin stress fiber formation and tensional force-induced stress fiber formation and reinforcement (PubMed : 26823019). Also acts downstream of ROCK kinase activation as part of a positive feedback mechanism in response to cellular mechanical stress loading (PubMed : 26823019). Organization and orientation of KRT18 filaments are responsible for the properly elongated morphology of epithelial tubules (By similarity). Involved in the uptake of thrombin-antithrombin complexes by hepatic cells (By similarity). When phosphorylated, plays a role in filament reorganization. Involved in the delivery of mutated CFTR to the plasma membrane. Together with KRT8, is involved in interleukin-6 (IL-6)-mediated barrier protection. See full target information KRT18
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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