Anti-Cytokeratin 5 + 14 antibody [16.4],Abcam,AB16570
Cytokeratin proteins can be useful markers for tumor identification and classification. Belonging to the type A (acidic) subfamily of low molecular weight keratins and existing in combination with keratin 5, keratin 14 distinguishes stratified epithelial cells from simple epithelial cells and is useful in identification of squamous cell carcinomas. It is considered a prognostic marker in breast carcinomas.
Host
Mouse
Reactivity
Human
Application
IHC-Fr, ICC/IF, WB
Platform ID
BAB964405123
Abcam
Contact
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Product Specifications
Scientific Background
Specifications
NameAnti-Cytokeratin 5 + 14 antibody [16.4]
Cat. No.AB16570
HostMouse
IsotypeIgG2a
ReactivityHuman
ApplicationIHC-Fr, ICC/IF, WB
ClonalityMonoclonal
Clone Number16.4
Concentration1 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A/G
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.08% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Required for the formation of keratin intermediate filaments in the basal epidermis and maintenance of the skin barrier in response to mechanical stress (PubMed : 11408584). Regulates the recruitment of Langerhans cells to the epidermis, potentially by modulation of the abundance of macrophage chemotactic cytokines, macrophage inflammatory cytokines and CTNND1 localization in keratinocytes (PubMed : 19267394). See full target information Krt5 Additional targets Keratin, type I cytoskeletal 14,Krt5,KRT14
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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