Anti-Cytokeratin 5 antibody [EP1601Y] - Cytoskeleton Marker,Abcam,AB52635

Anti-Cytokeratin 5 antibody [EP1601Y] - Cytoskeleton Marker (ab52635) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt (Intra), ICC/IF, IHC-P and WB. Anti-Cytokeratin 5 antibody [EP1601Y] - Cytoskeleton Marker (ab52635) was first used in a scientific publication in 1977 and has been cited over 163 times in peer reviewed journals. It's performance in IHC in mouse samples is trusted by the scientific community. Abcam's high quality manufacturing and validation processes ensure Anti-Cytokeratin 5 antibody [EP1601Y] - Cytoskeleton Marker (ab52635) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. Anti-Cytokeratin 5 antibody [EP1601Y] - Cytoskeleton Marker (ab52635) has 10 independent reviews from customers. Anti-Cytokeratin 5 antibody [EP1601Y] - Cytoskeleton Marker (ab52635) specifically detects Cytokeratin 5 (UniProt ID: P13647; Molecular weight: 63kDa) and is sold in 100 µL and 1 mL selling sizes. Conjugation-ready, carrier free format available for antibody clone EP1601Y - ab214586 . Antibody clone EP1601Y is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor ® 488, Alexa Fluor ® 647, HRP, APC, PE ( ab193894 , ab193895 , ab193896 , ab224984 , ab224985 ). Cytokeratin 5 (CK5) is a key diagnostic marker used to identify and classify certain cancers, such as basal-like breast carcinomas and squamous cell carcinomas. Its expression is linked to high-grade tumors and poorer prognosis in various cancers, including urothelial and colorectal cancers. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Mouse, Rat, Human

Application

IHC-P, Flow Cyt (Intra), ICC/IF, WB

Platform ID

BAB714480087

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Cytokeratin 5 antibody [EP1601Y] - Cytoskeleton Marker
Cat. No.AB52635
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationIHC-P, Flow Cyt (Intra), ICC/IF, WB
ClonalityMonoclonal
Clone NumberEP1601Y
Concentration0.118 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Required for the formation of keratin intermediate filaments in the basal epidermis and maintenance of the skin barrier in response to mechanical stress (By similarity). Regulates the recruitment of Langerhans cells to the epidermis, potentially by modulation of the abundance of macrophage chemotactic cytokines, macrophage inflammatory cytokines and CTNND1 localization in keratinocytes (By similarity). See full target information Keratin, type II cytoskeletal 5

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.