Anti-DDX4 / MVH antibody,Abcam,AB13840
Anti-DDX4 / MVH antibody (ab13840) is a rabbit polyclonal antibody and is validated for use in ICC/IF, IHC-Fr, IHC-P, WB. Anti-DDX4 / MVH antibody (ab13840) has been cited over 526 times in peer reviewed journals and is trusted by the scientific community. Abcam's high quality validation processes ensure Anti-DDX4 / MVH antibody (ab13840) has high sensitivity and specificity. Anti-DDX4 / MVH antibody (ab13840) has 22 independent reviews from customers. Anti-DDX4 / MVH antibody (ab13840) specifically detects DDX4 / MVH (UniProt ID: Q9NQI0; Molecular weight: 79kDa) and is sold in 100 µg selling sizes. DDX4, also known as MVH, is a crucial germ cell marker and RNA helicase involved in spermatogenesis. Utilizing DDX4 / MVH antibodies can significantly enhance the detection and study of germ cell development. Research indicates that DDX4 plays a vital role in maintaining germline integrity and repressing transposable elements, making it essential for reproductive biology.
Host
Rabbit
Reactivity
Mouse, Human
Application
ICC/IF, IHC-Fr, IHC-P, WB
Platform ID
BAB592216273
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data ATP-dependent RNA helicase required during spermatogenesis (PubMed : 10920202, PubMed : 21034600). Required to repress transposable elements and preventing their mobilization, which is essential for the germline integrity (By similarity). Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons (By similarity). Involved in the secondary piRNAs metabolic process, the production of piRNAs in fetal male germ cells through a ping-pong amplification cycle (By similarity). Required for PIWIL2 slicing-triggered piRNA biogenesis : helicase activity enables utilization of one of the slice cleavage fragments generated by PIWIL2 and processing these pre-piRNAs into piRNAs (By similarity). See full target information DDX4
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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