Anti-DDX4 / MVH antibody [mAbcam27591],Abcam,AB27591

What is this antibody validated in? Anti-DDX4 / MVH antibody [mAbcam27591] (ab27591) is a mouse monoclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P), Immunohistochemistry (IHC-Fr), Immunocytochemistry/immunofluorescence (ICC/IF) in Common marmoset, Human, Mouse samples. What is the molecular weight of DDX4 / MVH? Anti-DDX4 / MVH [mAbcam27591] (ab27591) specifically detects a band for DDX4 / MVH (UniProt: Q9NQI0) at a molecular weight of 76kDa. Trusted by the scientific community Anti-DDX4 / MVH [mAbcam27591] (ab27591) was first used in a scientific publication in 2012 and has been cited over 100 times in peer-reviewed journals. Reviewed by scientists Anti-DDX4 / MVH [mAbcam27591] (ab27591) has over 5 independent reviews from customers. Other related products We have a range of other formats of antibody clone [mAbcam27591] also available for your convenience: ab27591, Carrier free - ab180462 , HRP - ab196709 Want a custom formulation? This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact [email protected]

Host

Mouse

Reactivity

Mouse, Human, Pig, Common marmoset

Application

IHC-P, ICC/IF, WB, IHC-Fr

Platform ID

BAB029784990

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-DDX4 / MVH antibody [mAbcam27591]
Cat. No.AB27591
HostMouse
IsotypeIgG1
ReactivityMouse, Human, Pig, Common marmoset
ApplicationIHC-P, ICC/IF, WB, IHC-Fr
ClonalityMonoclonal
Clone NumbermAbcam27591
Concentration1 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 6.97% L-Arginine
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data ATP-dependent RNA helicase required during spermatogenesis (PubMed : 10920202, PubMed : 21034600). Required to repress transposable elements and preventing their mobilization, which is essential for the germline integrity (By similarity). Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons (By similarity). Involved in the secondary piRNAs metabolic process, the production of piRNAs in fetal male germ cells through a ping-pong amplification cycle (By similarity). Required for PIWIL2 slicing-triggered piRNA biogenesis : helicase activity enables utilization of one of the slice cleavage fragments generated by PIWIL2 and processing these pre-piRNAs into piRNAs (By similarity). See full target information DDX4

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