Anti-DNA Polymerase Kappa/POLK antibody,Abcam,AB115625
Host
Goat
Reactivity
Human
Application
IHC-P
Platform ID
BAB221126895
Abcam
Contact
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Product Specifications
Scientific Background
Specifications
NameAnti-DNA Polymerase Kappa/POLK antibody
Cat. No.AB115625
HostGoat
IsotypeIgG
ReactivityHuman
ApplicationIHC-P
ClonalityPolyclonal
Concentration1 - 1.4 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human POLK aa 800-850 conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Preservative: 0.01% Sodium azide Constituents: 0.88% Sodium chloride, 0.424% Tripotassium orthophosphate
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Depending on the context, it inserts the correct base, but causes frequent base transitions, transversions and frameshifts. Lacks 3'-5' proofreading exonuclease activity. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but does not have lyase activity. See full target information POLK
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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