Anti-DNAJB6 antibody [EPR17122] - BSA and Azide free,Abcam,AB240346
ab240346 is the carrier-free version of ab198995 . Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies . Conjugation ready Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications. Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold. Compatibility This product is compatible with the Maxpar ® Antibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar ® is a trademark of Fluidigm Canada Inc.
Host
Rabbit
Reactivity
Mouse, Rat, Human
Application
ICC/IF, WB, IHC-P, Flow Cyt (Intra), IP
Platform ID
BAB408870528

Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70 (PubMed : 10954706, PubMed : 28233300). Plays an indispensable role in the organization of KRT8/KRT18 filaments (PubMed : 10954706). Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin (PubMed : 11896048, PubMed : 22366786). Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins (PubMed : 20159555, PubMed : 22366786). Also reduces cellular toxicity and caspase-3 activity (PubMed : 11896048).. Isoform B. Isoform B but not isoform A inhibits huntingtin aggregation. See full target information DNAJB6
Category Paths
- Products>Primary Antibodies>IHC Antibodies
- Products>Primary Antibodies>Recombinant Antibodies
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