Anti-DNAJB6 antibody [EPR17122] - N-terminal,Abcam,AB198995

What is this antibody validated in? Anti-DNAJB6 antibody [EPR17122] - N-terminal (ab198995) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunoprecipitation (IP), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse, Rat samples. What is the molecular weight of DNAJB6? Anti-DNAJB6 [EPR17122] - N-terminal (ab198995) specifically detects a band for DNAJB6 (UniProt: O75190) at a molecular weight of 36kDa. Trusted by the scientific community Anti-DNAJB6 [EPR17122] - N-terminal (ab198995) was first used in a scientific publication in 2015 and has been cited over 10 times in peer-reviewed journals. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Other related products We have a range of other formats of antibody clone [EPR17122] also available for your convenience: ab198995, Carrier free - ab240346 , Alexa Fluor® 488 - ab322167 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Mouse, Rat, Human

Application

Flow Cyt (Intra), WB, ICC/IF, IHC-P, IP

Platform ID

BAB721376775

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-DNAJB6 antibody [EPR17122] - N-terminal
Cat. No.AB198995
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationFlow Cyt (Intra), WB, ICC/IF, IHC-P, IP
ClonalityMonoclonal
Clone NumberEPR17122
Concentration2.42 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70 (PubMed : 10954706, PubMed : 28233300). Plays an indispensable role in the organization of KRT8/KRT18 filaments (PubMed : 10954706). Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin (PubMed : 11896048, PubMed : 22366786). Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins (PubMed : 20159555, PubMed : 22366786). Also reduces cellular toxicity and caspase-3 activity (PubMed : 11896048).. Isoform B. Isoform B but not isoform A inhibits huntingtin aggregation. See full target information DNAJB6

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.