Anti-DR4 antibody [DR-4-02] - Low endotoxin, Azide free,Abcam,AB14738
Host
Mouse
Reactivity
Human
Application
Flow Cyt, ICC/IF
Platform ID
BAB473050971
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Product Specifications
Scientific Background
Specifications
NameAnti-DR4 antibody [DR-4-02] - Low endotoxin, Azide free
Cat. No.AB14738
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationFlow Cyt, ICC/IF
ClonalityMonoclonal
Clone NumberDR-4-02
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human TNFRSF10A. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Receptor for the cytotoxic ligand TNFSF10/TRAIL (PubMed : 26457518, PubMed : 38532423). The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis (PubMed : 19090789). Promotes the activation of NF-kappa-B (PubMed : 9430227). See full target information TNFRSF10A
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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