Anti-DR5 antibody,Abcam,AB16329
Host
Rabbit
Reactivity
Rat, Human
Application
ICC, WB
Platform ID
BAB035582206
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Product Specifications
Scientific Background
Specifications
NameAnti-DR5 antibody
Cat. No.AB16329
HostRabbit
IsotypeIgG
ReactivityRat, Human
ApplicationICC, WB
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.05% Sodium azide Constituents: PBS, 0.1% BSA
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Receptor for the cytotoxic ligand TNFSF10/TRAIL (PubMed : 10549288). The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis. See full target information TNFRSF10B
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
Request a product
Please provide the required information below so that we can quickly source your products.