Anti-DUS2L antibody [EPR14042],Abcam,AB181262

Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Human

Application

Flow Cyt (Intra), WB, IP, ICC/IF

Platform ID

BAB286306858

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-DUS2L antibody [EPR14042]
Cat. No.AB181262
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationFlow Cyt (Intra), WB, IP, ICC/IF
ClonalityMonoclonal
Clone NumberEPR14042
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Catalyzes the NADPH-dependent synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (PubMed : 15994936, PubMed : 26429968, PubMed : 30149704, PubMed : 34798057, PubMed : 38680565). Specifically modifies U20 in cytoplasmic tRNAs (PubMed : 38680565). Activity depends on the presence of guanosine at position 19 in the tRNA substrate (PubMed : 38680565). Negatively regulates the activation of EIF2AK2/PKR (PubMed : 18096616). See full target information DUS2

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