Anti-Deptor antibody,Abcam,AB103298

Host

Rabbit

Reactivity

Mouse, Human

Application

WB

Platform ID

BAB468353227

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-Deptor antibody
Cat. No.AB103298
HostRabbit
IsotypeIgG
ReactivityMouse, Human
ApplicationWB
ClonalityPolyclonal
Concentration0.5 mg/mL Batch dependent concentration
ImmunogenRecombinant Full Length Protein corresponding to Human DEPTOR.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Negative regulator of the mTORC1 and mTORC2 complexes : inhibits the protein kinase activity of MTOR, thereby inactivating both complexes (PubMed : 19446321, PubMed : 22017875, PubMed : 22017876, PubMed : 22017877, PubMed : 25936805, PubMed : 29382726, PubMed : 34519268, PubMed : 34519269). DEPTOR inhibits mTORC1 and mTORC2 to induce autophagy (PubMed : 22017875, PubMed : 22017876, PubMed : 22017877). In contrast to AKT1S1/PRAS40, only partially inhibits mTORC1 activity (PubMed : 34519268, PubMed : 34519269). See full target information DEPTOR

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.