Anti-Deptor antibody [EPR26159-220] - BSA and Azide free,Abcam,AB309532

Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies . Conjugation ready Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications. Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold. Compatibility This product is compatible with the Maxpar ® Antibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar ® is a trademark of Fluidigm Canada Inc.

Host

Rabbit

Reactivity

Human, Rat

Application

IP, WB, IHC-P

Platform ID

BAB718378215

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Deptor antibody [EPR26159-220] - BSA and Azide free
Cat. No.AB309532
HostRabbit
IsotypeIgG
ReactivityHuman, Rat
ApplicationIP, WB, IHC-P
ClonalityMonoclonal
Clone NumberEPR26159-220
Concentration1.023 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Constituents: PBS
Storage+4°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Negative regulator of the mTORC1 and mTORC2 complexes : inhibits the protein kinase activity of MTOR, thereby inactivating both complexes (PubMed : 19446321, PubMed : 22017875, PubMed : 22017876, PubMed : 22017877, PubMed : 25936805, PubMed : 29382726, PubMed : 34519268, PubMed : 34519269). DEPTOR inhibits mTORC1 and mTORC2 to induce autophagy (PubMed : 22017875, PubMed : 22017876, PubMed : 22017877). In contrast to AKT1S1/PRAS40, only partially inhibits mTORC1 activity (PubMed : 34519268, PubMed : 34519269). See full target information DEPTOR

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