Anti-Detyrosinated alpha Tubulin antibody [AA12] - Loading Control,Abcam,AB254154

What is this antibody validated in? Anti-Detyrosinated alpha Tubulin antibody [AA12] - Microtubule Marker (ab254154) is a mouse recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P), Immunohistochemistry (IHC-Fr), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse, Rat samples. What is the molecular weight of Detyrosinated alpha Tubulin? Anti-Detyrosinated alpha Tubulin [AA12] - Microtubule Marker (ab254154) specifically detects a band for Detyrosinated alpha Tubulin (UniProt: Q71U36) at a molecular weight of 50kDa. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies . Want a custom formulation? This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact [email protected]

Host

Mouse

Reactivity

Mouse, Rat, Human

Application

WB, IHC-P, ICC/IF, IHC-Fr

Platform ID

BAB531334246

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Detyrosinated alpha Tubulin antibody [AA12] - Loading Control
Cat. No.AB254154
HostMouse
IsotypeIgG2a
ReactivityMouse, Rat, Human
ApplicationWB, IHC-P, ICC/IF, IHC-Fr
ClonalityMonoclonal
Clone NumberAA12
Concentration0.882 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin. See full target information TUBA1A

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