Anti-Dihydrofolate reductase (DHFR) antibody,Abcam,AB152159

Host

Rabbit

Reactivity

Rat, Human

Application

IP, ICC/IF, WB, IHC-P

Platform ID

BAB282208826

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Dihydrofolate reductase (DHFR) antibody
Cat. No.AB152159
HostRabbit
IsotypeIgG
ReactivityRat, Human
ApplicationIP, ICC/IF, WB, IHC-P
ClonalityPolyclonal
Concentration1.54 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human Dihydrofolate reductase aa 1 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 Preservative: 0.025% Proclin 300 Constituents: PBS, 20% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds its own mRNA and that of DHFR2. See full target information Dihydrofolate reductase

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