Anti-Doublecortin antibody,Abcam,AB18723

Anti-Doublecortin antibody (ab18723) is a rabbit polyclonal antibody and is validated for use in ICC/IF, IHC-FoFr, IHC-Fr, IHC-P and WB. Anti-Doublecortin antibody (ab18723) was first used in a scientific publication in 2004 and has been cited over 474 times in peer reviewed journals. It's performance in Western blot and IHC in human, mouse and rat samples is trusted by the scientific community. Abcam's high quality validation processes ensure Anti-Doublecortin antibody (ab18723) has high sensitivity and specificity. Anti-Doublecortin antibody (ab18723) has 59 independent reviews from customers. Anti-Doublecortin antibody (ab18723) specifically detects Doublecortin (UniProt ID: O43602; Molecular weight: 41kDa) and is sold in 50 µg selling sizes. Doublecortin (DCX) is a critical protein in neuro research, particularly for its role in neuronal migration and neurogenesis. It is predominantly expressed in immature neurons and is essential for proper brain development. Researchers use doublecortin to study the formation and migration of new neurons, making it vital for understanding neurodevelopmental disorders and brain repair mechanisms. Its expression helps in assessing the dynamics of neuronal growth and the potential for neuroplasticity in various neurological conditions.

Host

Rabbit

Reactivity

Mouse, Rat, Quail

Application

WB, IHC-FoFr, IHC-P, IHC-Fr, ICC/IF

Platform ID

BAB472451259

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Doublecortin antibody
Cat. No.AB18723
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Quail
ApplicationWB, IHC-FoFr, IHC-P, IHC-Fr, ICC/IF
ClonalityPolyclonal
Concentration0.8 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Microtubule-associated protein required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCLK1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with PAFAH1B1/LIS-1 of overlapping, but distinct, signaling pathways that promote neuronal migration. See full target information DCX

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.