Anti-Dystrophin antibody [EPR23336-129],Abcam,AB275391

Product Specifications Anti-Dystrophin antibody [EPR23336-129] (ab275391) is a rabbit recombinant monoclonal antibody and is validated for use in IHC-Fr, IHC-P, mIHC in human, mouse and rat samples. Anti-Dystrophin antibody [EPR23336-129] (ab275391) specifically detects Dystrophin (UniProt ID: P11532; Molecular weight: 427kDa) and is sold in a convenient trial size to enable initial testing (20µL) and larger sizes for subsequent scaling up experiments (100 µL and 1 mL). Quality and Validation Abcam's high quality manufacturing and validation processes ensure Anti-Dystrophin antibody [EPR23336-129] (ab275391) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. Related Products Conjugation-ready, carrier free format available for antibody clone EPR23336-129 - ab275395 . Antibody clone EPR23336-129 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor® 647 ( ab282171 ). Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Mouse, Rat, Human

Application

mIHC, IHC-P, IHC-Fr

Platform ID

BAB037081486

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Dystrophin antibody [EPR23336-129]
Cat. No.AB275391
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationmIHC, IHC-P, IHC-Fr
ClonalityMonoclonal
Clone NumberEPR23336-129
Concentration0.5705 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Anchors the extracellular matrix to the cytoskeleton via F-actin. Ligand for dystroglycan. Component of the dystrophin-associated glycoprotein complex which accumulates at the neuromuscular junction (NMJ) and at a variety of synapses in the peripheral and central nervous systems and has a structural function in stabilizing the sarcolemma. Also implicated in signaling events and synaptic transmission. See full target information DMD

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