Anti-E Cadherin antibody [4A2] - BSA and Azide free,Abcam,AB233766
What is this antibody validated in? Anti-E Cadherin antibody [4A2] - BSA and Azide free (ab233766) is a mouse monoclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse, Rat samples. What is the molecular weight of E Cadherin? Anti-E Cadherin [4A2] - BSA and Azide free (ab233766) specifically detects a band for E Cadherin (UniProt: P12830) at a molecular weight of 97kDa. Specificity confirmed The specificity of Anti-E Cadherin antibody [4A2] - BSA and Azide free (ab233766) has been confirmed by Western blot testing in CDH1 Knockout A431 cells. Other related products We have a range of other formats of antibody clone [4A2] also available for your convenience: ab231303 , Carrier free - ab233766 Want a custom formulation? This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact [email protected] Conjugation ready Our carrier-free antibodies are typically supplied in a PBS-only formulation, purified and free of BSA, sodium azide and glycerol. This conjugation-ready format is designed for use with fluorochromes, metal isotopes, oligonucleotides, and enzymes, which makes them ideal for antibody labelling, functional and cell-based assays, flow-based assays (e.g. mass cytometry) and Multiplex Imaging applications. Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with 1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold. Compatibility This product is compatible with the Maxpar ® Antibody Labeling Kit from Fluidigm, without the need for antibody preparation. Maxpar ® is a trademark of Fluidigm Canada Inc.
Host
Mouse
Reactivity
Mouse, Rat, Human
Application
WB, ICC/IF, IHC-P
Platform ID
BAB037181438
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data CDH1 encodes a protein that is a calcium-dependent cell adhesion molecule, playing a role in cell-cell adhesion, mobility, and proliferation in epithelial cells. It acts as a potent invasive suppressor and serves as a ligand for integrin alpha-E/beta-7. The protein contributes to the sorting of heterogeneous cell types due to its homophilic interactions. E-Cad/CTF2, a product of CDH1, promotes the non-amyloidogenic degradation of Abeta precursors and strongly inhibits the production of APP C99 and C83. Additionally, in the context of microbial infection, it functions as a receptor for Listeria monocytogenes, with internalin A binding to it to promote bacterial uptake. This supplementary information is collated from multiple sources and compiled automatically. See full target information CDH1
Category Paths
- Products>Primary Antibodies>IHC Antibodies
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