Anti-E2F4 antibody [24E12],Abcam,AB314180

What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Human

Application

ICC/IF, Flow Cyt (Intra), IHC-P

Platform ID

BAB600112481

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-E2F4 antibody [24E12]
Cat. No.AB314180
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationICC/IF, Flow Cyt (Intra), IHC-P
ClonalityMonoclonal
Clone Number24E12
Concentration1.5 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human E2F4.
PurityAffinity purification
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 0.88% Sodium chloride
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3' found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DRTF1/E2F complex functions in the control of cell-cycle progression from G1 to S phase. E2F4 binds with high affinity to RBL1 and RBL2. In some instances can also bind RB1. Specifically required for multiciliate cell differentiation : together with MCIDAS and E2F5, binds and activate genes required for centriole biogenesis. See full target information E2F4

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.