Anti-EAAT2 antibody,Abcam,AB41621

What is this antibody validated in? Anti-EAAT2 antibody (ab41621) is a rabbit polyclonal antibody and is validated for use in Western Blot (WB) in Mouse, Rat samples. What is the molecular weight of EAAT2? Anti-EAAT2 (ab41621) specifically detects a band for EAAT2 (UniProt: P31596) at a molecular weight of 62kDa. Trusted by the scientific community Anti-EAAT2 (ab41621) was first used in a scientific publication in 2007 and has been cited over 80 times in peer-reviewed journals. Reviewed by scientists Anti-EAAT2 (ab41621) has over 5 independent reviews from customers.

Host

Rabbit

Reactivity

Mouse, Rat

Application

ICC, WB

Platform ID

BAB412768656

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-EAAT2 antibody
Cat. No.AB41621
HostRabbit
IsotypeIgG
ReactivityMouse, Rat
ApplicationICC, WB
ClonalityPolyclonal
Concentration0.8 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate (PubMed : 7557442, PubMed : 7698742, PubMed : 9373176). Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport (By similarity). Essential for the rapid removal of released glutamate from the synaptic cleft, and for terminating the postsynaptic action of glutamate (PubMed : 9180080). See full target information Slc1a2

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