Anti-EDR1 / PHC1 antibody [1F3F3],Abcam,AB175424

Host

Mouse

Reactivity

Human

Application

WB, Flow Cyt

Platform ID

BAB038680718

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-EDR1 / PHC1 antibody [1F3F3]
Cat. No.AB175424
HostMouse
IsotypeIgG2b
ReactivityHuman
ApplicationWB, Flow Cyt
ClonalityMonoclonal
Clone Number1F3F3
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human PHC1 aa 750 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.05% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Required for proper control of cellular levels of GMNN expression. See full target information PHC1

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