Anti-EEF2/Elongation factor 2 antibody [4B3-G7-H5],Abcam,AB131202

This product was changed from ascites to tissue culture supernatant on 17.08.2018. Please note that the dilutions may need to be adjusted accordingly. If you have any questions, please do not hesitate to contact our scientific support team.

Host

Mouse

Reactivity

Mouse, Rat, Human, African green monkey

Application

WB, ICC/IF

Platform ID

BAB038880622

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-EEF2/Elongation factor 2 antibody [4B3-G7-H5]
Cat. No.AB131202
HostMouse
IsotypeIgG2b
ReactivityMouse, Rat, Human, African green monkey
ApplicationWB, ICC/IF
ClonalityMonoclonal
Clone Number4B3-G7-H5
ImmunogenRecombinant Fragment Protein within Human EEF2. The exact immunogen used to generate this antibody is proprietary information.
PurityCross-flow filtration
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Catalyzes the GTP-dependent ribosomal translocation step during translation elongation (PubMed : 26593721). During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively (PubMed : 26593721). Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (PubMed : 26593721). See full target information EEF2

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