Anti-ENT1 antibody - N-terminal,Abcam,AB190877

Target data Uniporter involved in the facilitative transport of nucleosides and nucleobases, and contributes to maintaining their cellular homeostasis (PubMed : 10722669, PubMed : 10755314, PubMed : 12527552, PubMed : 14759222, PubMed : 15037197, PubMed : 17379602, PubMed : 21795683, PubMed : 26406980, PubMed : 27995448, PubMed : 35790189, PubMed : 8986748). Functions as a Na(+)-independent transporter (PubMed : 8986748). Involved in the transport of nucleosides such as adenosine, guanosine, inosine, uridine, thymidine and cytidine (PubMed : 10722669, PubMed : 10755314, PubMed : 12527552, PubMed : 14759222, PubMed : 15037197, PubMed : 17379602, PubMed : 26406980, PubMed : 8986748). Also transports purine nucleobases (hypoxanthine, adenine, guanine) and pyrimidine nucleobases (thymine, uracil) (PubMed : 21795683, PubMed : 27995448). Mediates basolateral nucleoside uptake into Sertoli cells, thereby regulating the transport of nucleosides in testis across the blood-testis barrier (By similarity). Regulates inosine levels in brown adipocytes tissues (BAT) and extracellular inosine levels, which controls BAT-dependent energy expenditure (PubMed : 35790189). See full target information SLC29A1