Anti-EPO-R antibody [EPR22366-40],Abcam,AB244202

Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Mouse, Rat

Application

IHC-P

Platform ID

BAB106959193

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-EPO-R antibody [EPR22366-40]
Cat. No.AB244202
HostRabbit
IsotypeIgG
ReactivityMouse, Rat
ApplicationIHC-P
ClonalityMonoclonal
Clone NumberEPR22366-40
Concentration0.489 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Receptor for erythropoietin, which mediates erythropoietin-induced erythroblast proliferation and differentiation (PubMed : 2539263, PubMed : 8341708, PubMed : 8382775, PubMed : 8617735). Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade (PubMed : 2539263, PubMed : 8382775, PubMed : 8617735). In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase (PubMed : 9573010). See full target information Epor

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