Anti-ERp57 antibody,Abcam,AB219393

Host

Goat

Reactivity

Mouse, Human

Application

IHC-P, WB, ICC/IF

Platform ID

BAB421164624

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-ERp57 antibody
Cat. No.AB219393
HostGoat
IsotypeIgG
ReactivityMouse, Human
ApplicationIHC-P, WB, ICC/IF
ClonalityPolyclonal
Concentration2 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human PDIA3 aa 300 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 20% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Protein disulfide isomerase that catalyzes the formation, isomerization, and reduction or oxidation of disulfide bonds in client proteins and functions as a protein folding chaperone (PubMed : 11825568, PubMed : 16193070, PubMed : 27897272, PubMed : 36104323, PubMed : 7487104). Core component of the major histocompatibility complex class I (MHC I) peptide loading complex where it functions as an essential folding chaperone for TAPBP. Through TAPBP, assists the dynamic assembly of the MHC I complex with high affinity antigens in the endoplasmic reticulum. Therefore, plays a crucial role in the presentation of antigens to cytotoxic T cells in adaptive immunity (PubMed : 35948544, PubMed : 36104323). See full target information PDIA3

Category Paths

Request a product

Please provide the required information below so that we can quickly source your products.