Anti-Enkephalin/ENK antibody,Abcam,AB77273

Host

Goat

Reactivity

Human

Application

WB, IHC-FoFr

Platform ID

BAB730072599

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Enkephalin/ENK antibody
Cat. No.AB77273
HostGoat
IsotypeIgG
ReactivityHuman
ApplicationWB, IHC-FoFr
ClonalityPolyclonal
Concentration0.5 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.3 Preservative: 0.02% Sodium azide Constituents: Tris buffered saline, 0.5% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Met-enkephalin. Neuropeptide that competes with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress.. Leu-enkephalin. Neuropeptide that competes with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress.. Met-enkephalin-Arg-Phe. Met-enkephalin-Arg-Phe neuropeptide acts as a strong ligand of Mu-type opioid receptor OPRM1. Met-enkephalin-Arg-Phe-binding to OPRM1 in the nucleus accumbens of the brain increases activation of OPRM1, leading to long-term synaptic depression of glutamate release.. PENK(114-133). Increases glutamate release in the striatum and decreases GABA concentration in the striatum.. PENK(237-258). Increases glutamate release in the striatum. See full target information PENK

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