Anti-EpCAM antibody [HEA125], prediluted,Abcam,AB46714

ab46714 reacts intensely with all carcinomas and metastased derived from the intestinal tract, stomach, pancreas, liver, lung, breast, ovary, thyroid gland, kidney, bladder, prostate. Stratified squamous epithelia usually stain less intensely than adenocarcinoma. The antibody is suitable for differentiation between carcinoma and non-carcinoma. Keratinizing areas of a tumour mass usually remain unstained, as do sarcoma, lymphoma, melanoma and neurogenic tumours.

Host

Mouse

Reactivity

Human

Application

ICC/IF

Platform ID

BAB356184565

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-EpCAM antibody [HEA125], prediluted
Cat. No.AB46714
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationICC/IF
ClonalityMonoclonal
Clone NumberHEA125
ImmunogenCell preparation containing EPCAM protein. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.3 Preservative: 0.09% Sodium azide Constituents: BSA, PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E. See full target information EPCAM

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