Anti-Ephrin A2 antibody [OTI3E3],Abcam,AB123877

The clone number has been updated from 3E3 to OTI3E3, both clone numbers name the same clone.

Host

Mouse

Reactivity

Human, African green monkey

Application

ICC/IF, IHC-P, Flow Cyt (Intra), WB

Platform ID

BAB044278030

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-Ephrin A2 antibody [OTI3E3]
Cat. No.AB123877
HostMouse
IsotypeIgG2b
ReactivityHuman, African green monkey
ApplicationICC/IF, IHC-P, Flow Cyt (Intra), WB
ClonalityMonoclonal
Clone NumberOTI3E3
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Full Length Protein corresponding to Human EFNA2.
PurityAffinity purification
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.3 Preservative: 0.02% Sodium azide Constituents: PBS, 50% Glycerol (glycerin, glycerine), 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. With the EPHA2 receptor may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis (By similarity). See full target information EFNA2

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