Anti-ErbB3 / HER3 antibody,Abcam,AB217206
Host
Rabbit
Reactivity
Rat, Human
Application
IHC-P
Platform ID
BAB107558905
Abcam
Contact
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Product Specifications
Scientific Background
Specifications
NameAnti-ErbB3 / HER3 antibody
Cat. No.AB217206
HostRabbit
IsotypeIgG
ReactivityRat, Human
ApplicationIHC-P
ClonalityPolyclonal
ImmunogenSynthetic Peptide within Human ERBB3 aa 650-750 conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.02% Proclin 300 Constituents: 50% Glycerol (glycerin, glycerine), 48.98% TBS, 1X, 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase (PubMed : 20682778). May also be activated by CSPG5 (PubMed : 15358134). Involved in the regulation of myeloid cell differentiation (PubMed : 27416908). See full target information ERBB3
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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