Anti-ErbB3 / HER3 antibody,Abcam,AB34641
Host
Rabbit
Reactivity
Human
Application
IP, ELISA, WB
Platform ID
BAB732571399
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Product Specifications
Scientific Background
Specifications
NameAnti-ErbB3 / HER3 antibody
Cat. No.AB34641
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationIP, ELISA, WB
ClonalityPolyclonal
Concentration2.5 mg/mL Batch dependent concentration
ImmunogenRecombinant Protein within Human ERBB3 aa 1250 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 Preservative: 0.01% Sodium azide Constituents: 0.88% Sodium chloride, 0.424% Potassium phosphate solution
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase (PubMed : 20682778). May also be activated by CSPG5 (PubMed : 15358134). Involved in the regulation of myeloid cell differentiation (PubMed : 27416908). See full target information ERBB3
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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