Anti-ErbB3 / HER3 antibody [EPR22669-25],Abcam,AB255607

What is this antibody validated in? Anti-ErbB3 / HER3 antibody [EPR22669-25] (ab255607) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunohistochemistry (IHC-P) in Human, Mouse samples. What is the molecular weight of ErbB3 / HER3? Anti-ErbB3 / HER3 [EPR22669-25] (ab255607) specifically detects a band for ErbB3 / HER3 (UniProt: P21860) at a molecular weight of 148kDa. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Other related products We have a range of other formats of antibody clone [EPR22669-25] also available for your convenience: ab255607, Carrier free - ab256504 , Alexa Fluor® 488 - ab322172 , ab324261 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents . What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies .

Host

Rabbit

Reactivity

Mouse, Human

Application

Flow Cyt (Intra), WB, IHC-P

Platform ID

BAB670090140

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-ErbB3 / HER3 antibody [EPR22669-25]
Cat. No.AB255607
HostRabbit
IsotypeIgG
ReactivityMouse, Human
ApplicationFlow Cyt (Intra), WB, IHC-P
ClonalityMonoclonal
Clone NumberEPR22669-25
Concentration0.53 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase (PubMed : 20682778). May also be activated by CSPG5 (PubMed : 15358134). Involved in the regulation of myeloid cell differentiation (PubMed : 27416908). See full target information ERBB3

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