Anti-ErbB3 / HER3 antibody [SP71],Abcam,AB93739

What is this antibody validated in? Anti-ErbB3 / HER3 antibody [SP71] (ab93739) is a rabbit recombinant monoclonal antibody and is validated for use in Flow Cytometry (Intra), Flow Cytometry (Flow Cyt), Immunohistochemistry (IHC-P), Multiplex IHC (mIHC) in Human samples. Collaboration Anti-ErbB3 / HER3 [SP71] (ab93739) is a clone from the portfolio of Spring Bioscience (Roche) SP clones which have been optimised for immunohistochemistry (IHC). Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 20µl. Discover our selection of trial-size antibodies. Other related products We have a range of other formats of antibody clone [SP71] also available for your convenience: ab93739, Carrier free - ab236220 , ab279498, ab302944, PE - ab306102 , APC - ab306103 , HRP - ab306104 , Alkaline Phosphatase - ab308990 , Alexa Fluor® 488 - ab309933 , Alexa Fluor® 647 - ab310300 , Alexa Fluor® 594 - ab310763 , Alexa Fluor® 555 - ab312290 , Alexa Fluor® 568 - ab312785 , Alexa Fluor® 750 - ab321776

Host

Rabbit

Reactivity

Human

Application

Flow Cyt (Intra), IHC-P, mIHC

Platform ID

BAB232621375

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-ErbB3 / HER3 antibody [SP71]
Cat. No.AB93739
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationFlow Cyt (Intra), IHC-P, mIHC
ClonalityMonoclonal
Clone NumberSP71
Concentration0.048 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A/G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.6 Preservative: 0.1% Sodium azide Constituents: PBS, 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it; ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase (PubMed : 20682778). May also be activated by CSPG5 (PubMed : 15358134). Involved in the regulation of myeloid cell differentiation (PubMed : 27416908). See full target information ERBB3

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