Anti-Estrogen Receptor beta 1 antibody [ERb455] - C-terminal,Abcam,AB187291

Host

Mouse

Reactivity

Human

Application

WB, Flow Cyt

Platform ID

BAB296701866

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-Estrogen Receptor beta 1 antibody [ERb455] - C-terminal
Cat. No.AB187291
HostMouse
IsotypeIgG2a
ReactivityHuman
ApplicationWB, Flow Cyt
ClonalityMonoclonal
Clone NumberERb455
Concentration0.2 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human ESR2. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Preservative: 0.05% Sodium azide Constituents: PBS, 0.05% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1/ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner (PubMed : 20074560).. Isoform 2. Lacks ligand binding ability and has no or only very low ERE binding activity resulting in the loss of ligand-dependent transactivation ability. See full target information ESR2

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