Anti-F-actin antibody [NH3],Abcam,AB205
Product Specifications Anti-F-actin antibody [NH3] (ab205) is a mouse monoclonal antibody and is validated for use in ELISA, Flow Cyt, ICC/IF, IHC-Fr, IHC-R, IP, WB in human, mouse, rabbit, rat samples. Anti-F-actin antibody [NH3] (ab205) specifically detects F-actin (UniProt ID: P60709; Molecular weight: 42kDa) and is sold in 250 µg selling sizes. Quality and Validation Abcam's high quality validation processes ensure Anti-F-actin antibody [NH3] (ab205) has high sensitivity and specificity. Anti-F-actin antibody [NH3] (ab205) has been cited over 126 times in peer reviewed journals and is trusted by the scientific community. Anti-F-actin antibody [NH3] (ab205) has 11 independent reviews from customers.
Host
Mouse
Reactivity
Rat, Rabbit, Human, Mouse
Application
IHC-Fr, Flow Cyt, ICC/IF, WB, ELISA, IHC-R
Platform ID
BAB297801338
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells (PubMed : 25255767, PubMed : 29581253). Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction (PubMed : 29581253). In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA (PubMed : 29925947). Part of the ACTR1A/ACTB filament around which the dynactin complex is built. The dynactin multiprotein complex activates the molecular motor dynein for ultra-processive transport along microtubules (By similarity). See full target information ACTB
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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