Anti-FACL4 antibody - Carboxyterminal end,Abcam,AB137525

Host

Rabbit

Reactivity

Mouse, Rat, Human

Application

IP, ICC/IF, WB, IHC-P

Platform ID

BAB485644923

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-FACL4 antibody - Carboxyterminal end
Cat. No.AB137525
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationIP, ICC/IF, WB, IHC-P
ClonalityPolyclonal
Concentration1.37 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human ACSL4 aa 600 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7 Preservative: 0.025% Proclin 300 Constituents: PBS, 20% Glycerol (glycerin, glycerine)
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoA for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed : 21242590, PubMed : 22633490, PubMed : 24269233). Preferentially activates arachidonate and eicosapentaenoate as substrates (PubMed : 21242590). Preferentially activates 8,9-EET > 14,15-EET > 5,6-EET > 11,12-EET. Modulates glucose-stimulated insulin secretion by regulating the levels of unesterified EETs (By similarity). Modulates prostaglandin E2 secretion (PubMed : 21242590). See full target information ACSL4

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