Anti-FAM46C antibody,Abcam,AB169699

Host

Mouse

Reactivity

Human

Application

WB

Platform ID

BAB424562992

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-FAM46C antibody
Cat. No.AB169699
HostMouse
IsotypeIgG
ReactivityHuman
ApplicationWB
ClonalityPolyclonal
Concentration0.5 mg/mL Batch dependent concentration
ImmunogenRecombinant Full Length Protein corresponding to Human TENT5C.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Catalyzes the transfer of one adenosine molecule from an ATP to an mRNA poly(A) tail bearing a 3'-OH terminal group and enhances mRNA stability and gene expression (PubMed : 28931820, PubMed : 32009146, PubMed : 34048638). Can also elongate RNA oligos ending with uridine molecule, provided that the sequence is adenosine-rich (PubMed : 34048638). Mainly targets mRNAs encoding endoplasmic reticulum-targeted protein (PubMed : 28931820).. (Microbial infection) Seems to enhance replication of some viruses, including yellow fever virus, in response to type I interferon. See full target information TENT5C

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