Anti-FGF 23 antibody [FGF23638],Abcam,AB190702

Host

Mouse

Reactivity

Human

Application

FuncS

Platform ID

BAB051874382

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-FGF 23 antibody [FGF23638]
Cat. No.AB190702
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationFuncS
ClonalityMonoclonal
Clone NumberFGF23638
ImmunogenRecombinant Full Length Protein corresponding to Human FGF23.
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.2 - 7.4 Constituents: BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Regulator of phosphate homeostasis (PubMed : 11062477). Inhibits renal tubular phosphate transport by reducing SLC34A1 levels (PubMed : 11409890). Up-regulates EGR1 expression in the presence of KL (By similarity). Acts directly on the parathyroid to decrease PTH secretion (By similarity). Regulator of vitamin-D metabolism (PubMed : 15040831). Negatively regulates osteoblast differentiation and matrix mineralization (PubMed : 18282132). See full target information FGF23

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