Anti-FKBP12 antibody [1E5-A12],Abcam,AB58072

What is this antibody validated in? Anti-FKBP12 antibody [1E5-A12] (ab58072) is a mouse monoclonal antibody and is validated for use in Western Blot (WB) in Human samples. What is the molecular weight of FKBP12? Anti-FKBP12 [1E5-A12] (ab58072) specifically detects a band for FKBP12 (UniProt: P62942) at a molecular weight of 12kDa.

Host

Mouse

Reactivity

Human

Application

WB

Platform ID

BAB620202833

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-FKBP12 antibody [1E5-A12]
Cat. No.AB58072
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationWB
ClonalityMonoclonal
Clone Number1E5-A12
ImmunogenRecombinant Full Length Protein corresponding to Human FKBP1A.
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand. Recruits SMAD7 to ACVR1B which prevents the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. May modulate the RYR1 calcium channel activity. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. See full target information FKBP1A

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