Anti-FKBP12 antibody,Abcam,AB24373
What is this antibody validated in? Anti-FKBP12 antibody (ab24373) is a rabbit polyclonal antibody and is validated for use in Western Blot (WB) in Human, Mouse, Rat samples. What is the molecular weight of FKBP12? Anti-FKBP12 (ab24373) specifically detects a band for FKBP12 (UniProt: P62942) at a molecular weight of 12kDa. Trusted by the scientific community Anti-FKBP12 (ab24373) was first used in a scientific publication in 2006 and has been cited over 10 times in peer-reviewed journals. Specificity confirmed The specificity of Anti-FKBP12 antibody (ab24373) has been confirmed by Western blot testing in FKBP1A Knockout HAP1 cells.
Host
Rabbit
Reactivity
Mouse, Rat, Human
Application
WB
Platform ID
BAB557721574
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Product Specifications
Scientific Background
Specifications
NameAnti-FKBP12 antibody
Cat. No.AB24373
HostRabbit
IsotypeIgG
ReactivityMouse, Rat, Human
ApplicationWB
ClonalityPolyclonal
Concentration0.9 mg/mL Batch dependent concentration
ImmunogenThe exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand. Recruits SMAD7 to ACVR1B which prevents the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. May modulate the RYR1 calcium channel activity. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. See full target information FKBP1A
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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