Anti-FKBP12 antibody,Abcam,AB2918

What is this antibody validated in? Anti-FKBP12 antibody (ab2918) is a rabbit polyclonal antibody and is validated for use in Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human samples. Trusted by the scientific community Anti-FKBP12 (ab2918) was first used in a scientific publication in 2003 and has been cited over 30 times in peer-reviewed journals. Reviewed by scientists Anti-FKBP12 (ab2918) has over 20 independent reviews from customers.

Host

Rabbit

Reactivity

Human

Application

IHC-P, ICC/IF

Platform ID

BAB870227821

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-FKBP12 antibody
Cat. No.AB2918
HostRabbit
IsotypeIgG
ReactivityHuman
ApplicationIHC-P, ICC/IF
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Human FKBP1A aa 1-50. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.05% Sodium azide Constituents: PBS, 0.1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand. Recruits SMAD7 to ACVR1B which prevents the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. May modulate the RYR1 calcium channel activity. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. See full target information FKBP1A

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