Anti-FKBP6 antibody [S05-4G2],Abcam,AB317425
Host
Rabbit
Reactivity
Human
Application
WB
Platform ID
BAB307896490

Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Has an essential role in spermatogenesis (PubMed : 36150389). It is required to repress transposable elements and prevent their mobilization, which is essential for the germline integrity (By similarity). Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons (By similarity). Acts as a co-chaperone via its interaction with HSP90 and is required for the piRNA amplification process, the secondary piRNA biogenesis (By similarity). May be required together with HSP90 in removal of 16 nucleotide ping-pong by-products from Piwi complexes, possibly facilitating turnover of Piwi complexes (By similarity). See full target information FKBP6
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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