Anti-FKLF / KLF11 antibody [OTI4H7],Abcam,AB279389

Host

Mouse

Reactivity

Human

Application

WB

Platform ID

BAB557921478

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-FKLF / KLF11 antibody [OTI4H7]
Cat. No.AB279389
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationWB
ClonalityMonoclonal
Clone NumberOTI4H7
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human KLF11 aa 1-300. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A/G
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.3 Preservative: 0.02% Sodium azide Constituents: 50% Glycerol (glycerin, glycerine), 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Transcription factor (PubMed : 10207080, PubMed : 9748269). Activates the epsilon- and gamma-globin gene promoters and, to a much lower degree, the beta-globin gene and represses promoters containing SP1-like binding inhibiting cell growth (PubMed : 10207080, PubMed : 16131492, PubMed : 9748269). Represses transcription of SMAD7 which enhances TGF-beta signaling (By similarity). Induces apoptosis (By similarity). See full target information KLF11

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