Anti-FOLR2 antibody [EM-35],Abcam,AB234190

Host

Mouse

Application

Flow Cyt

Platform ID

BAB184033444

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Product Specifications
Scientific Background

Specifications

NameAnti-FOLR2 antibody [EM-35]
Cat. No.AB234190
HostMouse
IsotypeIgG1
ApplicationFlow Cyt
ClonalityMonoclonal
Clone NumberEM-35
Concentration1 mg/mL Batch dependent concentration
ImmunogenCell preparation containing FOLR2 protein. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.0975% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. See full target information FOLR2

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