Anti-Factor XII antibody,Abcam,AB104557
Host
Goat
Reactivity
Human
Application
IHC-P
Platform ID
BAB173738388
Abcam
Contact
Tel: +44 (0)1223 696000
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Product Specifications
Scientific Background
Specifications
NameAnti-Factor XII antibody
Cat. No.AB104557
HostGoat
IsotypeIgG
ReactivityHuman
ApplicationIHC-P
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
PurityPrecipitation Ammonium Sulphate
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Constituents: 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, 0.238% HEPES
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa (PubMed : 2019570, PubMed : 21304106, PubMed : 8427954). See full target information F12
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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