Anti-Fas antibody,Abcam,AB82419
Host
Rabbit
Reactivity
Mouse, Rat
Application
WB
Platform ID
BAB550025270
Abcam
Contact
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Product Specifications
Scientific Background
Specifications
NameAnti-Fas antibody
Cat. No.AB82419
HostRabbit
IsotypeIgG
ReactivityMouse, Rat
ApplicationWB
ClonalityPolyclonal
Concentration1 mg/mL Batch dependent concentration
ImmunogenSynthetic Peptide within Mouse Fas conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Immunogen
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.09% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase CASP8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs CASP8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both (By similarity). See full target information Fas
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
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