Anti-Fas antibody,Abcam,AB216636
Host
Rabbit
Reactivity
Rat
Application
IHC-P
Platform ID
BAB925012776
Abcam
Contact
Tel: +44 (0)1223 696000
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Product Specifications
Scientific Background
Specifications
NameAnti-Fas antibody
Cat. No.AB216636
HostRabbit
IsotypeIgG
ReactivityRat
ApplicationIHC-P
ClonalityPolyclonal
ImmunogenSynthetic Peptide within Mouse Fas aa 1-100 conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein A
Appearance/FormLiquid
ShippingBlue Ice
FormulationpH: 7.4 Preservative: 0.02% Proclin 300 Constituents: 50% Glycerol (glycerin, glycerine), 48.98% TBS, 1X, 1% BSA
Storage-20°C
Regulatory StatusResearch Use Only
Scientific Background
Target data Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase CASP8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs CASP8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both (By similarity). See full target information Fas
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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