Anti-Fas antibody [EOS9.1] - Low endotoxin, Azide free,Abcam,AB185766
Endotoxin Level: Less than 0.001 ng/μg antibody, as determined by the LAL assay.
Host
Mouse
Reactivity
Human
Application
Flow Cyt
Platform ID
BAB175037764
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase CASP8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs CASP8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro). See full target information FAS
Category Paths
- Products>Primary Antibodies>Monoclonal Antibodies
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