Anti-Fibrinogen antibody,Abcam,AB34269
Anti-Fibrinogen antibody (ab34269) is a rabbit polyclonal antibody and is validated for use in FuncS, ICC/IF, IHC-P, sELISA in human, mouse samples. Anti-Fibrinogen antibody (ab34269) has been cited over 69 times in peer reviewed journals and is trusted by the scientific community. Abcam's high quality validation processes ensure Anti-Fibrinogen antibody (ab34269) has high sensitivity and specificity. Anti-Fibrinogen antibody (ab34269) has 12 independent reviews from customers. Anti-Fibrinogen antibody (ab34269) specifically detects Fibrinogen (UniProt ID: P02671; Molecular weight: 2kDa) and is sold in 125 µL selling sizes. Fibrinogen is a crucial protein involved in blood clotting and coagulation. Utilizing fibrinogen antibody can significantly enhance the detection and study of fibrinogen levels. Elevated fibrinogen levels are associated with increased risk of cardiovascular disease and inflammation, making it a vital biomarker for assessing health and disease.
Host
Rabbit
Reactivity
Human, Rabbit, Mouse
Application
sELISA, FuncS, ICC/IF, IHC-P
Platform ID
BAB803148770
Abcam
Contact
Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215
Email:
Specifications
Scientific Background
Target data Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the immune response via both innate and T-cell mediated pathways. See full target information FGA
Category Paths
- Products>Primary Antibodies>Polyclonal Antibodies
- Products>Primary Antibodies>IHC Antibodies
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