Anti-Fibulin 5 antibody [1G6A4],Abcam,AB66339

This product was changed from ascites to supernatant. Lot no's high than GR171104-21 are from Tissue Culture Supernatant

Host

Mouse

Reactivity

Human

Application

WB, IHC-P, ICC/IF

Platform ID

BAB991192259

Abcam

Headquarters

Discovery Drive Cambridge Biomedical Campus Cambridge CB2 0AX UK

Abcam

Contact

Tel: +44 (0)1223 696000
Fax: +44 (0)1223 215 215

Email:

[email protected]

Product Specifications
Scientific Background

Specifications

NameAnti-Fibulin 5 antibody [1G6A4]
Cat. No.AB66339
HostMouse
IsotypeIgG1
ReactivityHuman
ApplicationWB, IHC-P, ICC/IF
ClonalityMonoclonal
Clone Number1G6A4
Concentration1 mg/mL Batch dependent concentration
ImmunogenRecombinant Fragment Protein within Human FBLN5 aa 200 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.
PurityAffinity purification Protein G
Appearance/FormLiquid
ShippingBlue Ice
FormulationPreservative: 0.05% Sodium azide Constituents: PBS
Storage-20°C
Regulatory StatusResearch Use Only

Scientific Background

Target data Essential for elastic fiber formation, is involved in the assembly of continuous elastin (ELN) polymer and promotes the interaction of microfibrils and ELN (PubMed : 18185537). Stabilizes and organizes elastic fibers in the skin, lung and vasculature (By similarity). Promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. Vascular ligand for integrin receptors which may play a role in vascular development and remodeling (PubMed : 10428823). May act as an adapter that mediates the interaction between FBN1 and ELN (PubMed : 17255108). See full target information FBLN5

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